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Climb Bio, Inc. shares new results from its first clinical trial for CLYM116.

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Climb Bio reported lasting APRIL suppression and reductions in IgA-related measures, with no serious safety problems. These healthy-volunteer Phase 1 results support CLYM116, but patient results are still pending.

CLYM · Climb Bio, Inc.

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The findings give Climb Bio more evidence that CLYM116 can keep its target suppressed for longer, which may allow dosing every 12 weeks. The tests were in healthy volunteers, so they do not show whether the treatment helps people with kidney disease. The ongoing patient trial must answer that, and a Phase 3 study still depends on regulatory feedback.

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