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Nkarta, Inc. shared early results for its NKX019 treatment for myositis and systemic sclerosis.

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Nkarta reported promising responses to NKX019 in small groups of patients with myositis and systemic sclerosis, with no treatment-related deaths or treatment stops. The results are early, and two lower-dose myositis patients later had increased disease activity.

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The results suggest NKX019 may help people with myositis and systemic sclerosis, including patients who had tried other treatments. Safety findings also support the results: none of the 40 treated patients died or stopped treatment because of side effects. The evidence is still early. The strongest response counts came from small groups, and two lower-dose myositis patients later had increased disease activity and needed more treatment. This makes the results promising, but not proof that the therapy will work broadly.

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